In Situ Genetic Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells Using Engineered Zinc Finger Nucleases

The combination of induced pluripotent stem (iPS) cell technology and targeted gene modification by homologous recombination (HR) represents a promising new approach to generate genetically corrected, patient-derived cells that could be used for autologous transplantation therapies. This strategy ha...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sebastiano, Vittorio, Maeder, Morgan L., Angstman, James F., Haddad, Bahareh, Khayter, Cyd, Yeo, Dana T., Goodwin, Mathew J., Hawkins, John S., Ramirez, Cherie L., Batista, Luis F.Z., Artandi, Steven E., Wernig, Marius, Joung, J. Keith
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285772/
https://ncbi.nlm.nih.gov/pubmed/21898685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.718
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