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Zinc-Finger Nucleases for Somatic Gene Therapy: The Next Frontier

Zinc-finger nucleases (ZFNs) are a powerful tool that can be used to edit the human genome ad libitum. The technology has experienced remarkable development in the last few years with regard to both the target site specificity and the engineering platforms used to generate zinc-finger proteins. As a...

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Autores principales: Rahman, Shamim H., Maeder, Morgan L., Joung, J. Keith, Cathomen, Toni
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159524/
https://ncbi.nlm.nih.gov/pubmed/21631241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.087
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