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Zinc-Finger Nucleases for Somatic Gene Therapy: The Next Frontier

Zinc-finger nucleases (ZFNs) are a powerful tool that can be used to edit the human genome ad libitum. The technology has experienced remarkable development in the last few years with regard to both the target site specificity and the engineering platforms used to generate zinc-finger proteins. As a...

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Detalhes bibliográficos
Main Authors: Rahman, Shamim H., Maeder, Morgan L., Joung, J. Keith, Cathomen, Toni
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159524/
https://ncbi.nlm.nih.gov/pubmed/21631241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.087
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