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Zinc-Finger Nucleases for Somatic Gene Therapy: The Next Frontier

Zinc-finger nucleases (ZFNs) are a powerful tool that can be used to edit the human genome ad libitum. The technology has experienced remarkable development in the last few years with regard to both the target site specificity and the engineering platforms used to generate zinc-finger proteins. As a...

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Bibliographic Details
Main Authors: Rahman, Shamim H., Maeder, Morgan L., Joung, J. Keith, Cathomen, Toni
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159524/
https://ncbi.nlm.nih.gov/pubmed/21631241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.087
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