Evaluation of OPEN Zinc Finger Nucleases for Direct Gene Targeting of the ROSA26 Locus in Mouse Embryos

Zinc finger nucleases (ZFNs) enable precise genome modification in a variety of organisms and cell types. Commercial ZFNs were reported to enhance gene targeting directly in mouse zygotes, whereas similar approaches using publicly available resources have not yet been described. Here we report preci...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Hermann, Mario, Maeder, Morgan L., Rector, Kyle, Ruiz, Joseph, Becher, Burkhard, Bürki, Kurt, Khayter, Cyd, Aguzzi, Adriano, Joung, J. Keith, Buch, Thorsten, Pelczar, Pawel
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435328/
https://ncbi.nlm.nih.gov/pubmed/22970113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041796
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы