Evaluation of OPEN Zinc Finger Nucleases for Direct Gene Targeting of the ROSA26 Locus in Mouse Embryos

Zinc finger nucleases (ZFNs) enable precise genome modification in a variety of organisms and cell types. Commercial ZFNs were reported to enhance gene targeting directly in mouse zygotes, whereas similar approaches using publicly available resources have not yet been described. Here we report preci...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hermann, Mario, Maeder, Morgan L., Rector, Kyle, Ruiz, Joseph, Becher, Burkhard, Bürki, Kurt, Khayter, Cyd, Aguzzi, Adriano, Joung, J. Keith, Buch, Thorsten, Pelczar, Pawel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435328/
https://ncbi.nlm.nih.gov/pubmed/22970113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041796
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