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Translocation Capture Sequencing: A Method for High Throughput Mapping of Chromosomal Rearrangements

Chromosomal translocations require formation and joining of DNA double strand breaks (DSBs). These events disrupt the integrity of the genome and are involved in producing leukemias, lymphomas and sarcomas. Translocations are frequent, clonal and recurrent in mature B cell lymphomas, which bear a pa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Oliveira, Thiago, Resch, Wolfgang, Jankovic, Mila, Casellas, Rafael, Nussenzweig, Michel C., Klein, Isaac A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285106/
https://ncbi.nlm.nih.gov/pubmed/22033343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.10.007
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