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Translocation Capture Sequencing: A Method for High Throughput Mapping of Chromosomal Rearrangements

Chromosomal translocations require formation and joining of DNA double strand breaks (DSBs). These events disrupt the integrity of the genome and are involved in producing leukemias, lymphomas and sarcomas. Translocations are frequent, clonal and recurrent in mature B cell lymphomas, which bear a pa...

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Bibliografische gegevens
Hoofdauteurs: Oliveira, Thiago, Resch, Wolfgang, Jankovic, Mila, Casellas, Rafael, Nussenzweig, Michel C., Klein, Isaac A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285106/
https://ncbi.nlm.nih.gov/pubmed/22033343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.10.007
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