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Translocation Capture Sequencing: A Method for High Throughput Mapping of Chromosomal Rearrangements
Chromosomal translocations require formation and joining of DNA double strand breaks (DSBs). These events disrupt the integrity of the genome and are involved in producing leukemias, lymphomas and sarcomas. Translocations are frequent, clonal and recurrent in mature B cell lymphomas, which bear a pa...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285106/ https://ncbi.nlm.nih.gov/pubmed/22033343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.10.007 |
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