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Translocation Capture Sequencing: A Method for High Throughput Mapping of Chromosomal Rearrangements

Chromosomal translocations require formation and joining of DNA double strand breaks (DSBs). These events disrupt the integrity of the genome and are involved in producing leukemias, lymphomas and sarcomas. Translocations are frequent, clonal and recurrent in mature B cell lymphomas, which bear a pa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Oliveira, Thiago, Resch, Wolfgang, Jankovic, Mila, Casellas, Rafael, Nussenzweig, Michel C., Klein, Isaac A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285106/
https://ncbi.nlm.nih.gov/pubmed/22033343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.10.007
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