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Translocation Capture Sequencing: A Method for High Throughput Mapping of Chromosomal Rearrangements

Chromosomal translocations require formation and joining of DNA double strand breaks (DSBs). These events disrupt the integrity of the genome and are involved in producing leukemias, lymphomas and sarcomas. Translocations are frequent, clonal and recurrent in mature B cell lymphomas, which bear a pa...

詳細記述

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書誌詳細
主要な著者: Oliveira, Thiago, Resch, Wolfgang, Jankovic, Mila, Casellas, Rafael, Nussenzweig, Michel C., Klein, Isaac A.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285106/
https://ncbi.nlm.nih.gov/pubmed/22033343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.10.007
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