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The Origin of B cell Recurrent Chromosomal Translocations: Proximity vs. DNA damage

B cell lymphomas are characterized by recurrent chromosomal translocations. Why these events are so prevalent is an area of active investigation. Several ideas have been put forward to try to explain this phenomenon, including: nuclear proximity between translocating genes; repeated DNA damage by en...

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Bibliografische gegevens
Hoofdauteurs: Casellas, Rafael, Resch, Wolfgang, Hakim, Ofir, Nussenzweig, Michel C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818721/
https://ncbi.nlm.nih.gov/pubmed/23932709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.07.020
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