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The Origin of B cell Recurrent Chromosomal Translocations: Proximity vs. DNA damage

B cell lymphomas are characterized by recurrent chromosomal translocations. Why these events are so prevalent is an area of active investigation. Several ideas have been put forward to try to explain this phenomenon, including: nuclear proximity between translocating genes; repeated DNA damage by en...

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Detalles Bibliográficos
Autores principales: Casellas, Rafael, Resch, Wolfgang, Hakim, Ofir, Nussenzweig, Michel C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818721/
https://ncbi.nlm.nih.gov/pubmed/23932709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.07.020
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