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53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma
Deficiencies in factors that regulate the DNA damage response enhance the incidence of malignancy by destabilizing the genome. However, the precise influence of the DNA damage response on regulation of cancer-associated rearrangements is not well defined. Here we examine the genome-wide impact of tu...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658150/ https://ncbi.nlm.nih.gov/pubmed/23290917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.11.029 |
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