53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma

Deficiencies in factors that regulate the DNA damage response enhance the incidence of malignancy by destabilizing the genome. However, the precise influence of the DNA damage response on regulation of cancer-associated rearrangements is not well defined. Here we examine the genome-wide impact of tu...

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Bibliografiske detaljer
Main Authors: Jankovic, Mila, Feldhahn, Niklas, Oliveira, Thiago Y., Silva, Israel T., Kieffer-Kwon, Kyong-rim, Yamane, Arito, Resch, Wolfgang, Klein, Isaac, Robbiani, Davide F., Casellas, Rafael, Nussenzweig, Michel C.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658150/
https://ncbi.nlm.nih.gov/pubmed/23290917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.11.029
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