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Self-microemulsifying drug-delivery system for improved oral bioavailability of probucol: preparation and evaluation

The objective of our investigation was to design a self-microemulsifying drug-delivery system (SMEDDS) to improve the bioavailability of probucol. SMEDDS was composed of probucol, olive oil, Lauroglycol FCC, Cremophor EL, Tween-80, and PEG-400. Droplet sizes were determined. In vitro release was inv...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sha, Xianyi, Wu, Juan, Chen, Yanzuo, Fang, Xiaoling
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282610/
https://ncbi.nlm.nih.gov/pubmed/22359449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S28052
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