Preparation and Characterization of Self-Microemulsifying Drug Delivery System of Olmesartan Medoxomil for Bioavailability Improvement

Olmesartan medoxomil (OLM) is an angiotensin II receptor blocker (ARB) antihypertensive agent administered orally that has absolute bioavailability of only 26% due to the poor aqueous solubility (7.75 μg/ml). The aim of the present investigation was to develop a self-microemulsifying drug delivery s...

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Bibliographic Details
Published in:J Pharm (Cairo)
Main Authors: Prajapati, Shailesh T., Joshi, Harsh A., Patel, Chhaganbhai N.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595970/
https://ncbi.nlm.nih.gov/pubmed/26555991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/728425
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