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Self-microemulsifying drug-delivery system for improved oral bioavailability of probucol: preparation and evaluation
The objective of our investigation was to design a self-microemulsifying drug-delivery system (SMEDDS) to improve the bioavailability of probucol. SMEDDS was composed of probucol, olive oil, Lauroglycol FCC, Cremophor EL, Tween-80, and PEG-400. Droplet sizes were determined. In vitro release was inv...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Dove Medical Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282610/ https://ncbi.nlm.nih.gov/pubmed/22359449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S28052 |
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