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Self-microemulsifying drug-delivery system for improved oral bioavailability of pranlukast hemihydrate: preparation and evaluation

The purpose of the present investigation was to develop and evaluate a self-microemulsifying drug delivery system (SMEDDS) for improving the oral absorption of a pranlukast hemihydrate (PLH), a very poorly water-soluble drug. An efficient self-microemulsifying vehicle for PLH was selected and optimi...

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Autori principali: Baek, Myoung-Ki, Lee, Jong-Hwa, Cho, Young-Ho, Kim, Hak-Hyung, Lee, Gye-Won
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544354/
https://ncbi.nlm.nih.gov/pubmed/23326192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S37338
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