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Improving dissolution and oral bioavailability of pranlukast hemihydrate by particle surface modification with surfactants and homogenization

The present study was carried out to develop an oral formulation of pranlukast hemihydrate with improved dissolution and oral bioavailability using a surface-modified microparticle. Based on solubility measurements, surface-modified pranlukast hemihydrate microparticles were manufactured using the s...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Ha, Eun-Sol, Baek, In-hwan, Yoo, Jin-Wook, Jung, Yunjin, Kim, Min-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484661/
https://ncbi.nlm.nih.gov/pubmed/26150699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S87738
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