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Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process

In the present study, solid dispersion nanoparticles with a hydrophilic polymer and surfactant were developed using the supercritical antisolvent (SAS) process to improve the dissolution and oral absorption of megestrol acetate. The physicochemical properties of the megestrol acetate solid dispersio...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Ha, Eun-Sol, Kim, Jeong-Soo, Baek, In-hwan, Yoo, Jin-Wook, Jung, Yunjin, Moon, Hyung Ryong, Kim, Min-Soo
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531043/
https://ncbi.nlm.nih.gov/pubmed/26345723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S90706
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