Design of a gelatin microparticle-containing self-microemulsifying formulation for enhanced oral bioavailability of dutasteride

In this study, a gelatin microparticle-containing self-microemulsifying formulation (SMF) was developed using a spray-drying method to enhance the oral delivery of the poorly water-soluble therapeutic dutasteride. The effect of the amount of gelatin and the type and amount of hydrophilic additives,...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Baek, In-hwan, Ha, Eun-Sol, Yoo, Jin-Wook, Jung, Yunjin, Kim, Min-Soo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484659/
https://ncbi.nlm.nih.gov/pubmed/26150696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86458
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