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Design of a gelatin microparticle-containing self-microemulsifying formulation for enhanced oral bioavailability of dutasteride

In this study, a gelatin microparticle-containing self-microemulsifying formulation (SMF) was developed using a spray-drying method to enhance the oral delivery of the poorly water-soluble therapeutic dutasteride. The effect of the amount of gelatin and the type and amount of hydrophilic additives,...

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Détails bibliographiques
Publié dans:Drug Des Devel Ther
Auteurs principaux: Baek, In-hwan, Ha, Eun-Sol, Yoo, Jin-Wook, Jung, Yunjin, Kim, Min-Soo
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484659/
https://ncbi.nlm.nih.gov/pubmed/26150696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86458
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