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Self-microemulsifying drug delivery system for improved oral bioavailability of oleanolic acid: design and evaluation
Oleanolic acid is a poorly water-soluble drug with low oral bioavailability. A self-microemulsifying drug delivery system (SMEDDS) has been developed to enhance the solubility and oral bioavailability of oleanolic acid. The formulation design was optimized by solubility assay, compatibility tests, a...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Dove Medical Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3743642/ https://ncbi.nlm.nih.gov/pubmed/23966781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S47510 |
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