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Preparation and Characterization of Self-Microemulsifying Drug Delivery System of Olmesartan Medoxomil for Bioavailability Improvement

Olmesartan medoxomil (OLM) is an angiotensin II receptor blocker (ARB) antihypertensive agent administered orally that has absolute bioavailability of only 26% due to the poor aqueous solubility (7.75 μg/ml). The aim of the present investigation was to develop a self-microemulsifying drug delivery s...

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Detalhes bibliográficos
Publicado no:J Pharm (Cairo)
Main Authors: Prajapati, Shailesh T., Joshi, Harsh A., Patel, Chhaganbhai N.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595970/
https://ncbi.nlm.nih.gov/pubmed/26555991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/728425
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