Large Aggregates Are the Major Soluble Aβ Species in AD Brain Fractionated with Density Gradient Ultracentrifugation

Soluble amyloid-β (Aβ) aggregates of various sizes, ranging from dimers to large protofibrils, have been associated with neurotoxicity and synaptic dysfunction in Alzheimer's Disease (AD). To investigate the properties of biologically relevant Aβ species, brain extracts from amyloid β protein p...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Sehlin, Dag, Englund, Hillevi, Simu, Barbro, Karlsson, Mikael, Ingelsson, Martin, Nikolajeff, Fredrik, Lannfelt, Lars, Pettersson, Frida Ekholm
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280222/
https://ncbi.nlm.nih.gov/pubmed/22355408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032014
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker