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Increased Number of Plasma B Cells Producing Autoantibodies Against Aβ(42) Protofibrils in Alzheimer’s Disease

The Alzheimer’s disease (AD)-related peptide amyloid-β (Aβ) has a propensity to aggregate into various assemblies including toxic soluble Aβ protofibrils. Several studies have reported the existence of anti-Aβ antibodies in humans. However, it is still debated whether levels of anti-Aβ antibodies ar...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Söllvander, Sofia, Ekholm-Pettersson, Frida, Brundin, Rose-Marie, Westman, Gabriel, Kilander, Lena, Paulie, Staffan, Lannfelt, Lars, Sehlin, Dag
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923756/
https://ncbi.nlm.nih.gov/pubmed/26401929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150236
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