Sensitive detection of Aβ protofibrils by proximity ligation - relevance for Alzheimer's disease

BACKGROUND: Protein aggregation plays important roles in several neurodegenerative disorders. For instance, insoluble aggregates of phosphorylated tau and of Aβ peptides are cornerstones in the pathology of Alzheimer's disease. Soluble protein aggregates are therefore potential diagnostic and p...

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Detalhes bibliográficos
Main Authors: Kamali-Moghaddam, Masood, Pettersson, Frida Ekholm, Wu, Di, Englund, Hillevi, Darmanis, Spyros, Lord, Anna, Tavoosidana, Gholamreza, Sehlin, Dag, Gustafsdottir, Sigrun, Nilsson, Lars NG, Lannfelt, Lars, Landegren, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959092/
https://ncbi.nlm.nih.gov/pubmed/20923550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-124
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