Sensitive detection of Aβ protofibrils by proximity ligation - relevance for Alzheimer's disease

BACKGROUND: Protein aggregation plays important roles in several neurodegenerative disorders. For instance, insoluble aggregates of phosphorylated tau and of Aβ peptides are cornerstones in the pathology of Alzheimer's disease. Soluble protein aggregates are therefore potential diagnostic and p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kamali-Moghaddam, Masood, Pettersson, Frida Ekholm, Wu, Di, Englund, Hillevi, Darmanis, Spyros, Lord, Anna, Tavoosidana, Gholamreza, Sehlin, Dag, Gustafsdottir, Sigrun, Nilsson, Lars NG, Lannfelt, Lars, Landegren, Ulf
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2010
Aiheet:
Methodology Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959092/
https://ncbi.nlm.nih.gov/pubmed/20923550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-124
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