Amyloid-β protofibril levels correlate with spatial learning in Arctic Alzheimer’s disease transgenic mice

Oligomeric assemblies of Amyloid-β (Aβ) are suggested to be central in the pathogenesis of Alzheimer’s disease, since levels of soluble Aβ much better correlate with the extent of cognitive dysfunctions than senile plaque counts do. Moreover, such Aβ species have been shown to be neurotoxic, to inte...

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Bibliographische Detailangaben
Hauptverfasser: Lord, Anna, Englund, Hillevi, Söderberg, Linda, Tucker, Stina, Clausen, Fredrik, Hillered, Lars, Gordon, Marcia, Morgan, Dave, Lannfelt, Lars, Pettersson, Frida Ekholm, Nilsson, Lars NG
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752010/
https://ncbi.nlm.nih.gov/pubmed/19215301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2008.06836.x
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