Amyloid-β protofibril levels correlate with spatial learning in Arctic Alzheimer’s disease transgenic mice

Oligomeric assemblies of Amyloid-β (Aβ) are suggested to be central in the pathogenesis of Alzheimer’s disease, since levels of soluble Aβ much better correlate with the extent of cognitive dysfunctions than senile plaque counts do. Moreover, such Aβ species have been shown to be neurotoxic, to inte...

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Detaylı Bibliyografya
Asıl Yazarlar: Lord, Anna, Englund, Hillevi, Söderberg, Linda, Tucker, Stina, Clausen, Fredrik, Hillered, Lars, Gordon, Marcia, Morgan, Dave, Lannfelt, Lars, Pettersson, Frida Ekholm, Nilsson, Lars NG
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752010/
https://ncbi.nlm.nih.gov/pubmed/19215301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2008.06836.x
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