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Role of analytical ultracentrifugation in assessing the aggregation of protein biopharmaceuticals
In developing and manufacturing protein biopharmaceuticals, aggregation is a parameter that needs careful monitoring to ensure the quality and consistency of the final biopharmaceutical drug product. The analytical method of choice used to perform this task is size-exclusion chromatography (SEC). Ho...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761066/ https://ncbi.nlm.nih.gov/pubmed/17025277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080368 |
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