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Role of analytical ultracentrifugation in assessing the aggregation of protein biopharmaceuticals

In developing and manufacturing protein biopharmaceuticals, aggregation is a parameter that needs careful monitoring to ensure the quality and consistency of the final biopharmaceutical drug product. The analytical method of choice used to perform this task is size-exclusion chromatography (SEC). Ho...

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Sonraí Bibleagrafaíochta
Príomhúdar: Berkowitz, Steven A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer-Verlag 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761066/
https://ncbi.nlm.nih.gov/pubmed/17025277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080368
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