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Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars
Biologics such as monoclonal antibodies are much more complex than small-molecule drugs, which raises challenging questions for the development and regulatory evaluation of follow-on versions of such biopharmaceutical products (also known as biosimilars) and their clinical use once patent protection...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3714370/ https://ncbi.nlm.nih.gov/pubmed/22743980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3746 |
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