Role of analytical ultracentrifugation in assessing the aggregation of protein biopharmaceuticals

Por Berkowitz, Steven A.
Publicado em 2006

The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies

Por Houde, Damian, Berkowitz, Steven A., Engen, John R.
Publicado em 2010

Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding

Por Houde, Damian, Peng, Yucai, Berkowitz, Steven A., Engen, John R.
Publicado em 2010

Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars

Por Berkowitz, Steven A., Engen, John R., Mazzeo, Jeffrey R., Jones, Graham B.
Publicado em 2012

Conformation and dynamics of biopharmaceuticals: transition of mass spectrometry-based tools from academe to industry

Por Kaltashov, Igor A., Bobst, Cedric E., Abzalimov, Rinat R., Berkowitz, Steven A., Houde, Damian
Publicado em 2009

An Interaction between DNA Polymerase and Helicase Is Essential for the High Processivity of the Bacteriophage T7 Replisome

Por Kulczyk, Arkadiusz W., Akabayov, Barak, Lee, Seung-Joo, Bostina, Mihnea, Berkowitz, Steven A., Richardson, Charles C.
Publicado em 2012

Investigating monoclonal antibody aggregation using a combination of H/DX-MS and other biophysical measurements

Por Iacob, Roxana E., Bou-Assaf, George M., Makowski, Lee, Engen, John R., Berkowitz, Steven A., Houde, Damian
Publicado em 2013

Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches

Por Bobst, Cedric E., Abzalimov, Rinat R., Houde, Damian, Kloczewiak, Marek, Mhatre, Rohin, Berkowitz, Steven A., Kaltashov, Igor A.
Publicado em 2008

Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis

Por Pepinsky, R Blake, Silvian, Laura, Berkowitz, Steven A, Farrington, Graham, Lugovskoy, Alexey, Walus, Lee, Eldredge, John, Capili, Allan, Mi, Sha, Graff, Christilyn, Garber, Ellen
Publicado em 2010