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Investigating monoclonal antibody aggregation using a combination of H/DX-MS and other biophysical measurements
To determine how structural changes in antibodies are connected with aggregation, the structural areas of an antibody prone to and/or impacted by aggregation must be identified. In this work the higher-order structure and biophysical properties of two different monoclonal antibody (mAb) monomers was...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970822/ https://ncbi.nlm.nih.gov/pubmed/24136070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23754 |
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