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Studying polyglutamine aggregation in Caenorhabditis elegans using an analytical ultracentrifuge equipped with fluorescence detection

This work explores the heterogeneity of aggregation of polyglutamine fusion constructs in crude extracts of transgenic Caenorhabditis elegans animals. The work takes advantage of the recent technical advances in fluorescence detection for the analytical ultracentrifuge. Further, new sedimentation ve...

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Bibliografiska uppgifter
I publikationen:Protein Sci
Huvudupphovsmän: Kokona, Bashkim, May, Carrie A., Cunningham, Nicole R., Richmond, Lynn, Jay Garcia, F., Durante, Julia C., Ulrich, Kathleen M., Roberts, Christine M., Link, Christopher D., Stafford, Walter F., Laue, Thomas M., Fairman, Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815402/
https://ncbi.nlm.nih.gov/pubmed/26647351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2854
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