Weak IgG self‐ and hetero‐association characterized by fluorescence analytical ultracentrifugation

Weak protein–protein interactions may be important to binding cooperativity. A panel of seven fluorescently labeled tracer monoclonal IgG antibodies, differing in variable (V) and constant (C) region sequences, were sedimented in increasing concentrations of unlabeled IgGs of identical, similar, and...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Yang, Danlin, Correia, John J., Stafford III, Walter F., Roberts, Christopher J., Singh, Sanjaya, Hayes, David, Kroe‐Barrett, Rachel, Nixon, Andrew, Laue, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Methods and Applications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032368/
https://ncbi.nlm.nih.gov/pubmed/29637644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3422
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