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IgG Charge: Practical and Biological Implications

Practically, IgG charge can contribute significantly to thermodynamic nonideality, and hence to solubility and viscosity. Biologically, IgG charge isomers exhibit differences in clearance and potency. It has been known since the 1930s that all immunoglobulins carry a weak negative charge in physiolo...

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Detalhes bibliográficos
Publicado no:Antibodies (Basel)
Main Authors: Yang, Danlin, Kroe-Barrett, Rachel, Singh, Sanjaya, Laue, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640702/
https://ncbi.nlm.nih.gov/pubmed/31544830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib8010024
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