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Sampling protein motion and solvent effect during ligand binding

An exhaustive description of the molecular recognition mechanism between a ligand and its biological target is of great value because it provides the opportunity for an exogenous control of the related process. Very often this aim can be pursued using high resolution structures of the complex in com...

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Détails bibliographiques
Auteurs principaux: Limongelli, Vittorio, Marinelli, Luciana, Cosconati, Sandro, La Motta, Concettina, Sartini, Stefania, Mugnaini, Laura, Da Settimo, Federico, Novellino, Ettore, Parrinello, Michele
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277130/
https://ncbi.nlm.nih.gov/pubmed/22238423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112181108
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