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Energetics and Structural Characterization of the large-scale Functional Motion of Adenylate Kinase
Adenylate Kinase (AK) is a signal transducing protein that regulates cellular energy homeostasis balancing between different conformations. An alteration of its activity can lead to severe pathologies such as heart failure, cancer and neurodegenerative diseases. A comprehensive elucidation of the la...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4325324/ https://ncbi.nlm.nih.gov/pubmed/25672826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08425 |
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