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Large-scale motions in the adenylate kinase solution ensemble: coarse-grained simulations and comparison with solution X-ray scattering

While coarse-grained (CG) simulations provide an efficient approach to identify small- and large-scale motions important to protein conformational transitions, coupling with appropriate experimental validation is essential. Here, by comparing small-angle X-ray scattering (SAXS) predictions from CG s...

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Detalhes bibliográficos
Main Authors: Daily, Michael D., Makowski, Lee, Phillips, George N., Cui, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375699/
https://ncbi.nlm.nih.gov/pubmed/22711968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphys.2011.08.015
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