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Sampling protein motion and solvent effect during ligand binding

An exhaustive description of the molecular recognition mechanism between a ligand and its biological target is of great value because it provides the opportunity for an exogenous control of the related process. Very often this aim can be pursued using high resolution structures of the complex in com...

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Detalhes bibliográficos
Main Authors: Limongelli, Vittorio, Marinelli, Luciana, Cosconati, Sandro, La Motta, Concettina, Sartini, Stefania, Mugnaini, Laura, Da Settimo, Federico, Novellino, Ettore, Parrinello, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277130/
https://ncbi.nlm.nih.gov/pubmed/22238423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112181108
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