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Heparin Activates PKR by Inducing Dimerization
Protein kinase R (PKR) is an interferon-induced kinase that plays a pivotal role in the innate immunity pathway. PKR is activated to undergo autophosphorylation upon binding to double-stranded RNAs or RNAs that contain duplex regions. Activated PKR phosphorylates the α subunit of eukaryotic initiati...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268052/ https://ncbi.nlm.nih.gov/pubmed/21978664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.09.025 |
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