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Regulation of PKR by RNA: Formation of active and inactive dimers
PKR is a member of the eIF2α family of protein kinases that inhibit translational initiation in response to stress stimuli and functions as a key mediator of the interferon-induced antiviral response. PKR contains a dsRNA binding domain that bind to duplex regions present in viral RNAs, resulting in...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4641775/ https://ncbi.nlm.nih.gov/pubmed/26488609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01046 |
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