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Analysis of Monomeric and Dimeric Phosphorylated Forms of PKR

PKR (protein kinase R) is induced by interferon and is a key component of the innate immunity antiviral pathway. Upon binding dsRNA or dimerization in the absence of dsRNA, PKR undergoes autophosphorylation at multiple serines and threonines that activate the kinase. Although it has previously been...

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Bibliografski detalji
Glavni autori: Anderson, Eric, Quartararo, Christine, Brown, Raymond S., Shi, Yu, Yao, Xudong, Cole, James L.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819637/
https://ncbi.nlm.nih.gov/pubmed/20088595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901873p
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