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Analysis of PKR structure by small angle scattering
PKR (protein kinase R) is a key component of the interferon antiviral defense pathway. Upon binding dsRNA, PKR undergoes autophosphorylation reactions that activate the kinase. PKR contains an N-terminal double-stranded RNA binding domain (dsRBD), which consists of two tandem dsRNA binding motifs, a...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663012/ https://ncbi.nlm.nih.gov/pubmed/19232355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.02.019 |
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