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Analysis of Monomeric and Dimeric Phosphorylated Forms of PKR
PKR (protein kinase R) is induced by interferon and is a key component of the innate immunity antiviral pathway. Upon binding dsRNA or dimerization in the absence of dsRNA, PKR undergoes autophosphorylation at multiple serines and threonines that activate the kinase. Although it has previously been...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819637/ https://ncbi.nlm.nih.gov/pubmed/20088595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901873p |
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