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Analysis of PKR Activation Using Analytical Ultracentrifugation
PKR is a central component of the interferon antiviral defense pathway. Upon binding to dsRNA, PKR undergoes autophosphorylation reactions that activate the kinase, resulting in the inhibition of protein synthesis in virally-infected cells. We have used analytical ultracentrifugation and related bio...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2926283/ https://ncbi.nlm.nih.gov/pubmed/20533534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201000069 |
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