Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development

Hematopoietic stem cells (HSCs) interact with osteoblastic, stromal, and vascular components of the BM hematopoietic microenvironment (HM) that are required for the maintenance of long-term self-renewal in vivo. Osteoblasts have been reported to be a critical cell type making up the HSC niche in viv...

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Detaylı Bibliyografya
Asıl Yazarlar: Lane, Steven W., De Vita, Serena, Alexander, Kylie A., Karaman, Ruchan, Milsom, Michael D., Dorrance, Adrienne M., Purdon, Amy, Louis, Leeann, Bouxsein, Mary L., Williams, David A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2012
Konular:
Hematopoiesis and Stem Cells
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265198/
https://ncbi.nlm.nih.gov/pubmed/22123845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-368753
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