The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment

The p21-activated kinases (Paks) are serine/threonine kinases that are major effectors of the Rho guanosine 5′\x{2011}triphosphatase, Rac, and Cdc42. Rac and Cdc42 are known regulators of hematopoietic stem and progenitor cell (HSPC) function, however, a direct role for Paks in HSPCs has yet to be e...

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Bibliografische gegevens
Hoofdauteurs: Dorrance, Adrienne M., De Vita, Serena, Radu, Maria, Reddy, Pavankumar N. G., McGuinness, Meaghan K., Harris, Chad E., Mathieu, Ronald, Lane, Steven W., Kosoff, Rachelle, Milsom, Michael D., Chernoff, Jonathan, Williams, David A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2013
Onderwerpen:
Hematopoiesis and Stem Cells
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612857/
https://ncbi.nlm.nih.gov/pubmed/23335370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-460709
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