The gp130 cytokine IL-11 regulates engraftment of Vav1(−/−) hematopoietic stem and progenitor cells in lethally irradiated recipients

During bone marrow transplantation (BMT), hematopoietic stem and progenitor cells (HSPCs) respond to signals from the hematopoietic microenvironment (HM) by coordinately activating molecular pathways through Rho GTPases, including Rac. We have previously shown that deletion of Vav1, a hematopoietic-...

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Bibliografiske detaljer
Udgivet i:Stem Cells
Main Authors: De Vita, Serena, Li, Yanhua, Harris, Chad E., McGuinness, Meaghan K., Ma, Clement, Williams, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823755/
https://ncbi.nlm.nih.gov/pubmed/29235178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2760
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