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Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells
Wnt signaling controls early embryonic hematopoiesis and dysregulated β-catenin is implicated in leukemia. However, the role of Wnts and their source in adult hematopoiesis is still unclear, and is clinically important as upstream Wnt inhibitors enter clinical trials. We blocked Wnt secretion in hem...
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| Udgivet i: | Blood |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598194/ https://ncbi.nlm.nih.gov/pubmed/26089398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-598540 |
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