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Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells
Wnt signaling controls early embryonic hematopoiesis and dysregulated β-catenin is implicated in leukemia. However, the role of Wnts and their source in adult hematopoiesis is still unclear, and is clinically important as upstream Wnt inhibitors enter clinical trials. We blocked Wnt secretion in hem...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598194/ https://ncbi.nlm.nih.gov/pubmed/26089398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-598540 |
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