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SIRT1 is dispensable for function of hematopoietic stem cells in adult mice
SIRT1 is an NAD(+)-dependent histone deacetylase implicated in the establishment of the primitive hematopoietic system during mouse embryonic development. However, investigation of the role of SIRT1 in adult hematopoiesis has been complicated by the high perinatal mortality of SIRT1-deficient mice (...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Hematology
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293640/ https://ncbi.nlm.nih.gov/pubmed/22219225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-377077 |
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