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Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems

High levels of aldehyde dehydrogenase (ALDH) activity have been proposed to be a common feature of stem cells. Adult hematopoietic, neural, and cancer stem cells have all been reported to have high ALDH activity, detected using Aldefluor, a fluorogenic substrate for ALDH. This activity has been attr...

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Detalhes bibliográficos
Main Authors: Levi, Boaz P., Yilmaz, Ömer H., Duester, Gregg, Morrison, Sean J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647681/
https://ncbi.nlm.nih.gov/pubmed/18971422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-156752
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